Andrea S. Blevins Primeau, PhD, MBA

A 45-mg starting dose, reduced to 15 mg, produced the best outcome.

The combination produced 2 complete responses.

The overall response rate exceeded 60%, even in patients with severe disease.

Radiation therapy alone was highly effective for the treatment of Helicobacter pylori–independent gastric mucosa-associated lymphoid tissue lymphoma.

Patients with stage I to IIIA, HER2-positive breast cancer received trastuzumab alone or chemotherapy plus trastuzumab as adjuvant therapy.

Researchers identified risk factors for distant metastasis in sporadic and hereditary medullary thyroid cancer.

The analysis included a cohort of 28 patients with metastatic breast cancer with hTMB defined as 9 to 37 mutations per megabase, who were treated with pembrolizumab.

Baseline alcohol consumption was associated with a higher QOL score compared with never use of alcohol.

GPS can predict adverse outcomes in men with prostate cancer and may be used to select patients for active surveillance rather than active treatment.

A deepened understanding of long-term effects can help clinicians to better determine upfront therapy and monitoring strategies for pediatric patients with Hodgkin lymphoma.