Complications and Management of Coagulation Disorders in Leukemia Patients

CONCLUSION

In summary, coagulation disorders are common in leukemia. Thrombosis is as common as in solid malignancies. It is difficult to predict which patients will have bleeding and/or thrombosis. We need better predictors and coagulation tests to identify such patients. More research with prospective randomized control studies is needed on the role of novel oral anticoagulants, anticoagulant choice, dosing, and duration in hematologic malignancies.

Acknowledgments

The authors acknowledge the assistance of Dr Pankaj Malhotra, Dr Parathan Karunakaran, and Dr Ram Nampoothiri in providing the data related to the clinical vignettes and institutional data on coagulation disorders in leukemia patients.

Disclosure

The authors report no conflicts of interest in this work.

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Deepesh Lad, Arihant Jain, Subhash Varma

Department of Internal Medicine, Postgraduate Institute of Medical Education and Research, Chandigarh, India 

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Source: Blood and Lymphatic Cancer: Targets and Therapy.
Originally published September 18, 2017.