Caution Regarding Use of Buretrols to Administer Chemotherapy

We currently use buretrols to administer chemotherapy on our pediatric unit.  I had heard that this equipment is vented and therefore causes aerisolization of hazardous drug.  Is this true? — Name withheld on request

Yes, there is a vent or air valve on the buretrol that allows for chemotherapy vapors to escape (aerosolize).  This makes the device open and exposes staff, patients, and families to hazardous drug. Hence, the device would not be in compliance with <USP 800>.

These devices were often used to ensure timely drug delivery infusion rates. To minimize prolonged infusion times related to the IV pump or bag overfill, many facilities are weighing chemotherapy bags, including the percentage of overfill in the total volume, or allowing staff to increase infusion rates to ensure accurate completion times.